Alison J Hardcastle Selected Research

GTPase-Activating Proteins (GTPase-Activating Protein)

1/2017	Arl3 and RP2 regulate the trafficking of ciliary tip kinesins.
12/2012	Arl3 and RP2 mediated assembly and traffic of membrane associated cilia proteins.
2/2012	The X-linked retinitis pigmentosa protein RP2 facilitates G protein traffic.
4/2010	The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium.

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Alison J Hardcastle Research Topics

Disease

14	Retinitis Pigmentosa (Pigmentary Retinopathy) 11/2020 - 06/2002
5	Retinal Degeneration 01/2018 - 11/2014
5	Hereditary Corneal Dystrophies 01/2018 - 02/2002
3	Blue cone monochromatism 01/2022 - 12/2012
3	Retinal Dystrophies 02/2017 - 12/2016
2	Keratoconus 01/2021 - 09/2019
2	Retinal Diseases 01/2020 - 08/2016
2	Retinitis Pigmentosa 2 01/2017 - 04/2006
2	Color Vision Defects (Color Blindness) 01/2016 - 07/2010
2	Vision Disorders (Hemeralopia) 12/2013 - 05/2006
2	Cone Dystrophy 01/2012 - 07/2010
1	Low Vision (Subnormal Vision) 01/2022
1	Herpetic Keratitis 01/2021
1	1 Posterior Polymorphous Corneal Dystrophy 01/2020
1	Leber Congenital Amaurosis 01/2020
1	Corneal Diseases (Corneal Disease) 09/2019
1	Fuchs' Endothelial Dystrophy 01/2018
1	Craniofacial Abnormalities 04/2017
1	Brachydactyly 04/2017
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2017
1	Cataract (Cataracts) 01/2017
1	Ciliopathies 10/2016
1	Atrophy 05/2016
1	Bornholm Eye Disease 01/2016
1	Photophobia (Light Sensitivity) 01/2016
1	Epithelial Recurrent Erosion Dystrophy 04/2015
1	Glaucoma 01/2015
1	Corneal dystrophy and perceptive deafness 01/2015
1	Hypothermia 01/2014
1	Multiple Sclerosis 01/2014
1	Situs Inversus 08/2013
1	Megalocornea 02/2012
1	Nance-Horan syndrome 06/2010
1	Cone-Rod Dystrophies 05/2006
1	Neuroblastoma 06/2003
1	congenital stationary Night blindness 02/2003

Drug/Important Bio-Agent (IBA)

13	Retinaldehyde (Retinal)IBA 01/2022 - 02/2003
11	Proteins (Proteins, Gene)FDA Link 04/2017 - 06/2002
4	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 01/2017 - 04/2010
3	Cone OpsinsIBA 11/2014 - 07/2010
2	SteroidsIBA 01/2021 - 01/2017
2	ADP-Ribosylation Factors (ADP-Ribosylation Factor)IBA 01/2018 - 08/2013
2	Carrier Proteins (Binding Protein)IBA 01/2018 - 08/2013
2	Monomeric GTP-Binding ProteinsIBA 01/2017 - 02/2012
2	Nonsense Codon (Nonsense Mutation)IBA 01/2015 - 02/2012
2	SulfotransferasesIBA 01/2005 - 02/2002
2	CarbohydratesIBA 01/2005 - 02/2002
1	CollagenIBA 01/2021
1	Interleukin-8 (Interleukin 8)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Anaphase-Promoting Complex-Cyclosome Apc1 SubunitIBA 09/2019
1	Biomarkers (Surrogate Marker)IBA 09/2019
1	Collagen Type VIIBA 09/2019
1	diphosphoric acid (pyrophosphoric acid)IBA 01/2018
1	Biological ProductsIBA 02/2017
1	KinesinsIBA 01/2017
1	Protein Isoforms (Isoforms)IBA 01/2017
1	Blood Group Antigens (Blood Groups)IBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2016
1	GTP Phosphohydrolases (GTPases)IBA 01/2016
1	OpsinsIBA 01/2016
1	Collagen Type XVIIIBA 04/2015
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2014
1	CannabinoidsIBA 01/2014
1	Pharmaceutical PreparationsIBA 01/2014
1	RNA Precursors (Precursor, mRNA)IBA 08/2013
1	RNA (Ribonucleic Acid)IBA 08/2013
1	Membrane Proteins (Integral Membrane Proteins)IBA 12/2012
1	GTP-Binding Proteins (G-Protein)IBA 02/2012
1	chordinIBA 02/2012
1	Rod OpsinsIBA 07/2010
1	9-cis-retinalIBA 07/2010
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2008
1	Detergents (Detergent)IBA 06/2003
1	tubulin-specific chaperone CIBA 11/2002

Therapy/Procedure

4	Therapeutics 01/2020 - 12/2013
2	Corneal Transplantation (Keratoplasty) 01/2018 - 01/2015
1	Transjugular Intrahepatic Portasystemic Shunt 01/2017
1	Iridectomy 01/2015